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Associate Professor Stephen G. Mech, Ph.D. Chair Professor Karen A. Campbell, Ph.D., P. Kenneth Nase M.D. '55 Chair of Biology Professors Richard G. Heller, Ph.D. and Gerald L. Kreider, Ph.D. Associate Professors David T. Osgood, Ph.D., and Andrew I. Samuelsen, Ph.D. Assistant Professor Bryce Brylawski, Ph.D. Instructor Lara P. Zerkowski, M.S. '98 Lecturers Shelley Kauffman, Ph.D. and Susan C. Munch

FUSION A periodic newsletter about the sciences at Albright College
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Courses
BIO 101/102 Concepts and Connections in Biology This course is designed to enable non-science concentrators to develop an understanding and an appreciation for how science works from a biological perspective through study of select topics in natural sciences. We will examine current developments in topics such as genetics, human physiology, environmental biology and microbiology in a way that will allow students to construct a framework of key biological concepts and make connections to their lives through consideration of the applications of basic scientific principles. Students will become involved in the process of doing science, implementing lab exercises aimed at answering specific questions and developing their critical thinking skills. Evolution will be discussed as a unifying theme which helps to elevate biology from a bewildering collection of facts to a coherent study of changing life on a changing planet.
BIO 102 is very similar in scope to BIO 101 except for an emphasis on field biology. Three hours lecture and three hours laboratory per week.
BIO 125 Changing Face of Human Disease This is an exploration of emerging or reemergent infectious diseases in humans. Emergence of new strains of influenza, hepatitis C, SARS, and virulent strains of E. Coli are included along with proposed explanations for their emergence. Antibiotic resistance and also the immune system dysfunction associated with HIV/AIDS is also discussed. Skills in written and oral communication are stressed. Laboratory work includes current methods used to study disease-associated microorganisms. Satisfies the general studies laboratory science requirement. Not intended for biology concentrators. Three hours lecture and three hours laboratory per week.
BIO 190 Issues in Human Reproduction and Genetics This is a student-directed inquiry into issues involving human reproduction and genetics. After a general introduction to human embryology and genetics, students select topics for in-class presentations, discussions and a term paper. The course involves presentations by local experts in the field of human reproduction and genetics, as well as laboratory work in embryology. Emphasis is placed on developing a better understanding of the scientific and ethical theories underlying dilemmas associated with issues in this developing field. The course is designed to encourage students with varying viewpoints about this complex subject to better understand and their own feelings and help explore alternatives. Offered fall semester. Three hours lecture and three hours laboratory per week. General studies lab science. No prerequisites. Open to students in the College Honors program only.
BIO 201/202/203 General Biology This course introduces students to the biological sciences through a study of principles and concepts basic to the major disciplines of biology. Biology concentrators complete all three semesters.
BIO 201 General Biology I: Structure and Function This course introduces students to cellular biology, metabolism, biochemistry, anatomy, physiology and development. Three hours lecture, three hours laboratory per week, plus optional study/discussion sessions.
BIO 202 General Biology II: Systematics and Ecology (W) An introduction to plant and animal systematics, plant physiology and ecology, this course includes a major laboratory project and report. Three hours lecture and three hours laboratory per week.
BIO 203 General Biology III: Genetics and Evolution (W) An introduction to classical genetics, molecular genetics and population genetics, this course includes a major writing project designed to explore specific topics in genetics and evolution. Three hours lecture per week.
BIO 204 Anatomy & Physiology I This is a study of the fundamentals of human anatomy and physiology, with emphasis placed on the organization of the body, cells and tissues, integumentary system, skeletal system, muscular system, nervous system, and special senses.
This is the first semester of a two-semester course in anatomy and physiology. It will employ an integration of morphological and physiological aspects of the human body. This course is intended to provide a strong background in human anatomy and physiology for human biology students, science majors, and students with an interest in related allied health fields. Some basic concepts of biology and chemistry will be integrated with this course, which serve as a basis for developing specific concepts in anatomy and physiology.
BIO 300 Biometry This course teaches biology students how to design an experiment in a format that leads to a statistical analysis which tests the desired hypothesis. Students learn how to recognize and apply statistical analyses most appropriate for a given data set, focusing on real examples from recent or on-going research. Emphasis is placed on some of the more commonly used statistical methods in biology in order to provide a framework for exploration of more advanced methods. This is an applied course with emphasis on using computer programs effectively. Three hours lecture and two hours laboratory per week. Offered fall semester of odd years.
BIO 306 Anatomy and Physiology II This is a study of the fundamentals of human anatomy and physiology, with emphasis placed on the organization of the endocrine, cardiovascular, lymphatic, respiratory, digestive, urinary and reproductive systems.
This is the second semester of a two-semester course in anatomy and physiology. The second semester will again employ an integration of morphological and physiological aspects of the human body. This course is intended to provide a strong background in human anatomy and physiology for human biology students, science majors, and students with an interest in related allied health fields. All students are required to prepare a research paper on a specific area of study. This investigation will allow an in-depth study of a small area of a very large discipline.
Prerequisite: students must earn a quality grade in BIO 204 to enroll in this course
BIO 311 Ecology (W) This course studies the relationships between animals and plants and their natural environments. Factors shaping the distribution and abundance of organisms, populations and communities are discussed. Specific emphasis is given to factors such as competition, predation, herbivory, mutualism, physiology, climate, energy flow, and biochemical cycles that influence species adaptations and, in turn, patterns of distribution and abundance. The laboratory is designed to provide experience in the field using several techniques for monitoring both plant and animal populations, as well as environmental parameters in a variety of habitats. Three hours lecture and three hours laboratory per week. Offered fall semester.
Prerequisites: BIO 201, 202
BIO/EVS 312 Wetlands Ecology This course covers the ecology of freshwater and saltwater wetlands systems. Linkages between the plants, animals, microbes, hydrology and chemistry of various wetland types are emphasized. Wetland delineation, functional assessment of wetlands, and wetland creation and restoration are among the topics discussed. Field trips and laboratory sessions focus on quantitative evaluations of the hydrology, soils, and plant and animal communities of various wetland types. Three hours lecture and three hours laboratory per week. Offered fall semester of even years.
Prerequisite: BIO 202 or permission of the instructor
BIO 314 Botany and Plant Taxonomy Principles of identification and classification of land plants are discussed in this course. Plant keys and digital photography are used in the field and photomicroscopy in the lab complements field work. This course includes a survey of major vascular plant families and field study of local plants and vegetation types. Three hours lecture and three hours laboratory per week. Offered spring semester as needed.
Prerequisite: BIO 202 or permission of the instructor
BIO/EVS 315 Watershed Hydrology and Water Resources Water is perhaps our most vital resource, yet its availability is often taken for granted. This class covers the principles of hydrologic processes that govern water distribution within a variety of landscapes. The influence of land use (e.g. rural, agricultural, urban) on water availability and quality are addressed, as well as watershed management issues and practices. In the laboratory portion of this course, field techniques are used to quantify hydrologic processes in surface waters, groundwater and wetland soils.
Water quality is also assessed within lake and river environments. Modern tools, such as Geographic Information Systems (GIS), are used to connect landscape properties to water availability and quality. Three hours lecture and three hours laboratory per week. Offered fall semester of odd years.
Prerequisite: EVS 101 is recommended
BIO/EVS 316 Conservation Biology The study of preserving and restoring nature and ecosystem processes are covered. This course introduces students to the anthropogenic problems facing ecosystems and some of the possible solutions. Theory and application pertaining to biodiversity, species extinction, biological invasions, land management and other topics are discussed. Three hours lecture per week. Offered spring semester of odd years.
Prerequisite: BIO 202, BIO 311 recommended
BIO 317 Aquatic Ecophysiology This course will explore the interplay between the physiological mechanisms of organisms, and the ecological responses of populations to environmental stress. Topics covered will include basic physiological mechanisms, the effect of natural and human-induced environmental change on animal physiology, the special adaptations that allow organisms to survive in a variety of aquatic habitats, and the ecological implications of physiological responses to stress and environmental change. Three hours lecture and three hours lab per week.
Prerequisites: BIO 201 and 202
BIO 318 Marine and Aquatic Science Over 70 percent of the world is covered by water with about 97 percent of it in the oceans. Despite this, much of these aquatic environments are not well explored or understood. This is a problem since even though the underwater world may seem alien and distant, we are irrevocably interconnected with this ecosystem. From fisheries to deep ocean carbon dioxide pumping humanity's future is tied with the aquatic world. In this course you will be introduced to the general concepts of oceanography, limnology (the study of freshwater systems), and aquatic ecology. Through a series of fieldtrips and lab exercises, you will gain firsthand experience with the tools and techniques used to discover the secrets under the waves. This course includes a trip to a marine research lab during which you will run self-designed surveys and experiments to truly become aquatic scientists. Three hours lecture and three hours lab per week.
Prerequisites: BIO 311 and CHE 106
BIO 321 General Bacteriology This course introduces students to the fundamental concepts of microbiology. Physiology, genetics, immunology, medical bacteriology, virology and concepts of applied microbiology are discussed. Three hours lecture and three hours laboratory per week. Offered fall semester.
Prerequisites: BIO 201; 203; CHE 105, 106; and CHE 207, 208
BIO 323 Developmental Biology This course emphasizes topics relevant to vertebrate development. The lecture shows continuity between classical embryological work and modern experimental biology. The laboratory is divided between classical and experimental work. Three hours lecture and three hours laboratory per week. Offered spring semester.
Prerequisites: BIO 201, 203
BIO 324 Comparative Vertebrate Anatomy (W) This course emphasizes understanding the functional and comparative anatomy of the vertebrates through exploration of vertebrate structure and function from an evolutionary perspective. Protochordates, lamprey eel, shark, mudpuppy, and cat are dissected to compare the basic architectural patterns of vertebrate systems and to discover ways in which existing structural patterns are modifications of ancestral patterns. Three hours lecture and three hours laboratory per week. Offered spring semester of odd years.
Prerequisite: BIO 201
BIO 327 Histology and Microtechniques A study of tissue histology and ultrastructure, including an introduction to a number of methods for preparing material for study using light and electron microscopy, transmission electron microscopy, photomicroscopy, macrophotography, digital imaging and image processing. The course introduces students to research techniques and clinical procedures. It involves three hours lecture and two hours laboratory per week, plus additional lab time by arrangement. Offered fall semester.
Prerequisite: BIO 201
BIO 332 Cell Biology (W) This is an investigation into the many aspects of cell structure and function, including the importance of proteins and other macromolecules encountered within cells, as well as specific cellular organelles. Intracellular sorting, protein targeting and signal transduction are examined, along with the mechanisms involved in cancer and programmed cell death. Laboratory exercises introduce students to sterile cell culture techniques and the skills involved in establishing and manipulating plant tissue and animal cell cultures. Fluorescent and scanning Electron Microscopy, SDS PAGE and other techniques will be learned. Three hours lecture and three hours laboratory per week. Offered spring semester.
Prerequisites: BIO 201, 203 and CHE 207
BIO 334 Vertebrate Natural History This course is a survey of the natural history of the vertebrates. Students learn the ecology, evolution and the natural history of the major vertebrate classes including fish, amphibians, reptiles, birds and mammals. Laboratory focuses on taxonomic identification of vertebrates native to Pennsylvania and on various field techniques used to study and survey vertebrates. At least one field trip will be over a weekend. Offered spring semester of even years.
Prerequisite: BIO 202
BIO 342 Evolution this is a lecture class focusing on the role of evolution in shaping biological organisms. Major topics include natural selection, adaptation, evolution of life histories, population genetics, and the processes of speciation and macroevolution. Occasional discussions will center on reading current and seminal papers examining the important advances in evolutionary theory. Offered spring semester of even years.
Prerequisites: BIO 201 and 203
BIO 343 Molecular Genetics (W) In this course, students gain an understanding of the genetic systems of viruses, bacteria, protists, plants and animals in molecular terms. Areas of discussion include immunogenetics, transposition, gene cloning, control of gene expression and the molecular biology of developmental processes. Lab work emphasizes basic methods used for isolation, analysis and cloning of DNA molecules. Three hours lecture and three hours laboratory per week. Offered spring semester.
Prerequisites: BIO 201, BIO 203, CHE 207.
BIO 490 Behavioral Endocrinology Seminar (W) Students will investigate the interactions between hormones and behavior through the study of phenomena ranging from the molecular level to the social level. Behavioral endocrinology is studied from a comparative perspective by including examples from many different kinds of animals, to illuminate the various hormonal and behavioral mechanisms that have evolved in animals to deal with common problems of reproduction and survival. Offered in alternate years with BIO 493.
Prerequisite: BIO 201
BIO 491 Seminar on Special Topics (W) Discussions and written assignments provide an opportunity for exploration of specific topics in depth using a seminar format. Emphasis is placed on development of communication skills and ability to read and evaluate original scientific literature. Seminar topics include such areas as cell ultrastructure, immunobiology, neurobiology and environmental issues.
BIO 492 Environmental Biology Seminar A seminar concerning areas of biological research that have helped to describe, explain, or solve problems of adverse human impact on ecosystems. The main emphasis of this course is on freshwater biology, including water pollution and the introduction of non-native species.
BIO 493 Neuroethology: The Neural Basis of Behavior (W) This is a seminar course designed to integrate the results of behavioral field studies and neurobiological lab work. Problems of interest for written and oral assignments include signal detection, recognition, discrimination, localization, decision- making, coordination, orientation and the control of complex acts. Further areas of interest may include the neuronal and hormonal mechanisms underlying periodic changes in behavior, as well as the ontogeny and the evolution of behavior and its mechanisms. Offered in alternate years with BIO 490.
Prerequisite: BIO 201
BIO 494 Mammalian Evolution A seminar concerning the evolution of mammals. Lectures present an overview of mammalian evolution, interspersed with student presentations based on readings from current literature in the field. Students also design, develop, and provide a written proposal of a research project addressing some aspect of mammalian evolution.
BIO 495 Molecular Biology Seminar This course explores several different aspects of molecular biology, with an emphasis on plant molecular biology, and plant genetic engineering through the use of soil bacterium Agrobacterium tumefaciens. The genetic components of tumor-inducing plasmids of Agrobacterium and methods to engineer this plasmid to deliver genes of interest into a plant are described. Strategies to increase and control gene expression in genetically engineered plants are outlined, along with antibody production in transgenic plants, pathogen-derived resistance, virus resistance in plants, strategies for gene isolation and phytoremediation. An overview of immunology will be presented and human gene therapy is discussed along with issues of risk assessment, genetic containment and safety. Offered fall semester.
BIO 496 Scientific and Biomedical Imaging This is an overview of the use of imaging technologies in scientific data acquisition, medical diagnostics and communication. The seminar reviews the use of imaging from early microscopes, radiology, and photography to the current range of technologies from ultrastructural studies to modern medical imaging techniques, remote sensing, digital imaging and image processing. Laboratories use equipment available at Albright, including both scanning and transmission electron microscopes and provide opportunities to explore other facilities in the immediate area. Students are responsible for oral and written presentations, as well as an independent study project. The course involves three class sessions and a two-hour laboratory per week, plus additional laboratory work by arrangement. Offered spring semester.
BIO 498 Immunology Seminar (W) This course is an analysis of the vertebrate immune system, including antibody structure and function, Band T-cell function, immune response mechanisms, serology, immunogenetics and immunopathology. Written and oral assignments emphasize critical analysis and discussion of current journal articles in immunobiology. Three hours lecture and three hours laboratory per week. Offered fall semester.
Prerequisite: BIO 203 and either 321 or 343
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